PRP(Platelet Rich Plasma)
Platelet activation plays a key role in the process of wound and soft tissue healing. The use of platelet rich plasma (PRP), a portion of the patient’s own blood having a platelet concentration above baseline, to promote healing of injured tendons, ligaments, muscles, and joints, can be applied to various musculoskeletal problems..
PRP is a great therapeutic option for male and female patients experiencing hair loss.
It was used as early as the 1990s in maxillo-facial and plastic surgery. PRP injections are prepared from one to a few tubes of the patient’s own blood with strict aseptic technique. After being centrifuged, the activated platelets are injected into the abnormal tissue, releasing growth factors that recruit and increase the proliferation of reparative cells. Ultrasound imaging may or may not be used to guide the injection.In PRP your plasma with activated growth factors is inserted into your scalp .It improves the quality of hair and controls hairfall.
PRP contains special cells called Platelets, that can theoretically cause growth of the hair follicles by stimulating the stem cells and other cells in the microenvironment of the hair follicle. These special Platelet cells promote healing, accelerates the rate and degree of tissue healing and regeneration, responds to injury, and formation of new cellular growth.
PRP specific cells that causes hair growth include:
Platelet-Derived Growth Factor (PDGF)—promotes blood vessel growth, cell replication, skin formation;
Transforming Growth-Factor-Beta (TGF-b)—promotes growth of matrix between cells, bone metabolism;
Vascular Endothelial Growth Factor (VEGF)—promotes blood vessel formation;
Epidermal Growth Factor (EGF)—promotes cell growth and differentiation, blood vessel formation, collagen formation;
Fibroblast Growth Factor-2 (FGF-2)—promotes growth of specialized cells and blood vessel formation; and,
Insulin Like Growth Factor - (IGF)—a regulator of normal physiology in nearly every type of cell in the body
These growth factors provide direct nutrition to already existing hair follicles and reduce hairfall ,promote overall hair quality making them more thick and thus increasing there density as a whole.
PRP therapy offers the opportunity for hair growth for those patients who are not candidates for surgery or those patients wanting a more aggressive nonsurgical approach to treatment. For our surgical patients PRP therapy is performed at the same day as the hair restoration surgery.