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Intralesional steroid injection involves a corticosteroid, such as triamcinolone acetonide or betamethasone suspension, which is injected directly into a lesion on or immediately below the skin.

In New Zealand triamcinolone is marketed as Kenacort-A, and is available in 2 strengths: 10 mg per ml (Kenacort-A 10), or 40 mg per ml (Kenacort-A 40). Triamcinolone acetonide is marketed as Kenalog in the USA. Betamethasone injection is marketed as Celestone Chronodose (1 mL).

Shorter-acting corticosteroid preparations, such as dexamethasone or betamethasone acetate, are sometimes administered in combination with triamcinolone.

What are intralesional steroids used for?

Intralesional steroid injection may be indicated for the following skin conditions:
• alopecia areata
• discoid lupus erythematosus
• keloids/hypertrophic scars
• granuloma annulare
• Other granulomatous disorders such as cutaneous sarcoidosis or granuloma faciale
• hypertrophic lichen planus
• lichen simplex chronicus (neurodermatitis)
• localised psoriasis
• necrobiosis lipoidica
• acne cysts
• small infantile haemangiomas
• other localised inflammatory skin diseases